1005759-01-2Relevant articles and documents
Synthesis, characterization and catalytic activity of PEPPSI-type palladium–NHC complexes
?zdemir, Ismail,Gürbüz, Nevin,Hamdi, Naceur,Mansour, Lamjed,Slimani, Ichraf
, (2021)
Eight benzimidazolium salts (2a–h) with two nitrogen atoms substituted by various alkyl groups have been synthesized in high yields. The benzimidazolium salts were readily converted into the corresponding PEPPSI-type palladium–NHC complexes (PEPPSI = pyridine-enhanced precatalyst preparation, stabilization, and initiation) (3a–h). The structures of all compounds were characterized by 1H NMR, 13C NMR, and IR spectroscopy as well as by elemental analysis techniques, which support the proposed structures. The catalytic activity of the PEPPSI-type palladium–NHC complexes was evaluated with respect to the direct C5-arylation of 2-substituted heteroaryl derivatives (thiophene, furan and thiazole) with various aryl bromides. This arylation occurs efficiently and selectively at the C5-position of the 2-substituted thiophene, furan and thiazole derivatives.
Direct arylation (hetero-coupling) of heteroarenes via unsymmetrical palladium-PEPPSI-NHC type complexes
?zdemir, ?smail,Ashfaq, Muhammad,Gürbüz, Nevin,Karci, Hüseyin,Naveed Zafar, Muhammad,Nawaz Tahir, Muhammad,Nawaz, Zahid
, (2021/08/16)
The growing interest of industry in the field of bi(hetero)arenes compounds, motivated us to synthesize these compounds via homogeneous catalytic route by using Pd PEPPSI-type complexes through direct arylation. In this work, the five new Pd PEPPSI-type c
Arylation of heterocyclic compounds by benzimidazole-based N-heterocyclic carbene-palladium(II) complexes
?ahin, Neslihan,Gürbüz, Nevin,Karab?y?k, Hande,Karab?y?k, Hasan,?zdemir, ?smail
, (2019/12/25)
Specific C–H bond can be activated for arylation using aryl halide without the aid of directing the group in the case of electron-rich heteroarenes. The ability to readily generate halo substituted arylated heteroarenes is important in organic chemistry s
