1005763-48-3Relevant articles and documents
1-(2-Phenoxyphenyl)methanamines: SAR for dual serotonin/noradrenaline reuptake inhibition, metabolic stability and hERG affinity
Whitlock, Gavin A.,Blagg, Julian,Fish, Paul V.
, p. 596 - 599 (2008/09/20)
A novel series of 1-(2-phenoxyphenyl)methanamines is disclosed, which possess selective dual 5-HT and NA reuptake pharmacology. Analogues with good human in vitro metabolic stability, hERG selectivity and passive membrane permeability were identified.