100632-81-3

Basic information

• Product Name: ibutilide
• Synonyms: ibutilide
• CAS NO: 100632-81-3
• Molecular Weight: 384.583
• Mol File: 100632-81-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ibutilide(CAS DataBase Reference)
• NIST Chemistry Reference: ibutilide(100632-81-3)
• EPA Substance Registry System: ibutilide(100632-81-3)

Safety Data

• Hazardous Substances Data: 100632-81-3(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 2687-91-4 1-ethyl-2-pyrrolidinone 
• 1329598-91-5 4-(N-ethyl-N-heptylamino)butanoylchloride hydrochloride 
• 208402-95-3 4-(ethylamino)butanoic acid hydrochloride 
• 1329598-96-0 4-(N-ethyl-N-heptylamino)butanoic acid hydrochloride 
• 629-06-1 1-Chloroheptane 
• 130350-55-9 N-[{4-(N-ethyl-N-heptylamino)butanoyl}phenyl]methanesulfonamide 
• 863029-84-9 N-[4-(1-hydroxyallyl)phenyl]methanesulfonamide 
• 66793-76-8 ethyl(heptyl)amine 
• 201230-82-2 carbon monoxide 
• 100632-57-3 4-((methanesulfonyl)amino)-γ-oxobenzenebutanoic acid 
• 1197-22-4 N-phenylmethanesulfonamide 
• 83922-54-7 N-(4-formylphenyl)methanesulfonamide 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 122647-32-9 ibutilide hemifumarate 
• 145429-03-4 C₂₀H₃₅N₂O₂S⁽¹⁺⁾ 
• 130350-55-9 N-[{4-(N-ethyl-N-heptylamino)butanoyl}phenyl]methanesulfonamide 

Relevant articles and documents

A Multicatalytic Approach to the Hydroaminomethylation of α-Olefins

We report an approach to conducting the hydroaminomethylation of diverse α-olefins with a wide range of alkyl, aryl, and heteroarylamines at relatively low temperatures (70–80 °C) and pressures (1.0–3.4 bar) of synthesis gas. This approach is based on sim

HYDROAMINOMETHYLATION OF OLEFINS

The present invention relates to a method comprising the step of contacting under hydroaminomethylation conditions, an olefin, an amine, a rhodium-phosphorous ligand, and synthesis gas (syngas). In particular, it has been discovered that, under some circumstances, a neutral rhodium-monodentate phosphite ligand is prescribed. The invention provides a simple way of making, in high yields and regiospecificity, a variety of products, including pharmacologically active products such as ibutilide, terfenadine, and fexofenadine, and derivatives thereof.

Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides

The present invention provides novel sulfonanilide and benzene-alkylaminium compounds which are the products of processes utilizing novel intermediates. Both the novel compounds and the novel intermediates are useful for the therapeutic or prophylactic treatment of arrhythmic activity.