100648-29-1 Usage
Description
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 is a chemically stable, isosteric analog of Prostaglandin D2 (PGD2), wherein the 11-keto group is replaced by an exocyclic methylene. It is derived from PGH2 and is produced in the cerebrospinal fluid (CSF) by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a leukocyte-type PGD synthase.
Uses
Used in Pharmaceutical Industry:
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 is used as a stable analog of PGD2 for research and development purposes. It helps in understanding the biological activities and mechanisms of PGD2, which can be useful in the development of new drugs and therapies targeting prostaglandin pathways.
Used in Research Applications:
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 is used as a research tool for studying the biological effects and signaling pathways of PGD2. It can be employed in various experimental setups to investigate the role of PGD2 in different physiological and pathological processes.
Used in Drug Development:
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 can be used as a lead compound in the development of new drugs targeting the prostaglandin pathways. Its stable and isosteric nature makes it a promising candidate for further chemical modifications and optimization to enhance its therapeutic potential.
Used in Diagnostic Applications:
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 can be used as a diagnostic marker for various diseases and conditions associated with altered prostaglandin levels. Its stable nature makes it suitable for use in diagnostic assays and tests to monitor disease progression and treatment efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 100648-29-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,6,4 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100648-29:
(8*1)+(7*0)+(6*0)+(5*6)+(4*4)+(3*8)+(2*2)+(1*9)=91
91 % 10 = 1
So 100648-29-1 is a valid CAS Registry Number.
