1006585-49-4

Basic information

• Product Name: 1-(2,3-dichloro-4-((3-phenyl-1,2,4-oxadiazol-5-yl)methoxy)phenyl)-2-methylenebutan-1-one
• Synonyms: 1-(2,3-dichloro-4-((3-phenyl-1,2,4-oxadiazol-5-yl)methoxy)phenyl)-2-methylenebutan-1-one
• CAS NO: 1006585-49-4
• Molecular Weight: 403.265
• Mol File: 1006585-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2,3-dichloro-4-((3-phenyl-1,2,4-oxadiazol-5-yl)methoxy)phenyl)-2-methylenebutan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3-dichloro-4-((3-phenyl-1,2,4-oxadiazol-5-yl)methoxy)phenyl)-2-methylenebutan-1-one(1006585-49-4)
• EPA Substance Registry System: 1-(2,3-dichloro-4-((3-phenyl-1,2,4-oxadiazol-5-yl)methoxy)phenyl)-2-methylenebutan-1-one(1006585-49-4)

Safety Data

• Hazardous Substances Data: 1006585-49-4(Hazardous Substances Data)

Upstream product

• 613-92-3 N-hydroxybenzenecarboximidamide 
• 113239-57-9 <2,3-dichloro-4-(2-methylenebutyryl)phenoxy>acetyl chloride 
• 2350-46-1 2',3'-dichloro-4'-hydroxybutyrophenone 
• 1217-67-0 <2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid 
• 58-54-8 ethacrynic acid 

Relevant articles and documents

Environmental-protection preparation method for high yielding of 1,2,4-oxadiazole compounds containing alpha,beta-unsaturated ketones

The invention provides an environmental-protection preparation method for high yielding of 1,2,4-oxadiazole compounds containing alpha,beta-unsaturated ketones; with 2,3-dichlorophenol as a raw material, an intermediate 5 is obtained through methylation and protection of phenolic hydroxyl groups, Friedel-Crafts acylation, methyl protecting group removal, nucleophilic substitution, ester hydrolysis, aldol condensation and dehydration reaction and then undergoes cyclization reaction with substituted amine oxime to obtain the target products 6r, 6s and 6u. The method has the advantages of mild reaction conditions, has no use of first-class reagents and other reagents harmful on the environment and operating personnel, fewer by-products, stable and controllable reactions, simple postprocessing, high yield and purity, and easy industrialized production.