1006619-90-4

Basic information

• Product Name: 2-amino-5-chloro-N-cyclopropyl-3-methylbenzamide
• Synonyms: 2-amino-5-chloro-N-cyclopropyl-3-methylbenzamide
• CAS NO: 1006619-90-4
• Molecular Weight: 224.69
• Mol File: 1006619-90-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-amino-5-chloro-N-cyclopropyl-3-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-chloro-N-cyclopropyl-3-methylbenzamide(1006619-90-4)
• EPA Substance Registry System: 2-amino-5-chloro-N-cyclopropyl-3-methylbenzamide(1006619-90-4)

Safety Data

• Hazardous Substances Data: 1006619-90-4(Hazardous Substances Data)

Upstream product

• 120374-68-7 6-chloro-8-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 765-30-0 Cyclopropylamine 
• 18600-39-0 cyclopropylamine hydrochloride 
• 20776-67-4 2-amino-5-chloro-3-methylbenzoic acid 
• 1127-59-9 7-methyl-1H-indole-2,3-dione 
• 1132-03-2 2-(hydroxyimino)-N-(2-methylphenyl)acetamide 
• 95-53-4 o-toluidine 
• 4389-45-1 3-methylantranilic acid 

Downstream Products

• 1156541-11-5 N-(4-chloro-2-(cyclopropylcarbamoyl)-6-methylphenyl)-5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide 
• 1257069-37-6 C₂₃H₂₁Cl₂N₅O₄ 
• 1257069-53-6 C₂₂H₂₀Cl₂N₆O₃ 
• 1257069-84-3 C₂₃H₂₁Cl₂N₅O₄ 
• 1352547-78-4 C₂₂H₁₇Cl₂F₃N₆O₂S 
• 1392234-76-2 C₂₂H₁₇Cl₂F₃N₆O₃ 
• 1217506-14-3 C₂₂H₁₈Cl₂F₃N₅O₃ 
• 1352547-93-3 C₂₃H₁₉Cl₂F₃N₆O₃S 

Relevant articles and documents

Acyl thiourea and acyl urea derivatives containing trifluoromethylpyridine and application thereof

The invention discloses acyl thiourea and acyl urea derivatives containing trifluoromethylpyridine and an application thereof. A structure of the derivatives is shown in a general formula I. In the formula, definitions of R1, R2, R3, X and other groups are as shown in the description. The compound represented by the general formula I has excellent insecticidal activity, and can be used to preventand treat pests such as cotton bollworm, diamondback moth and brown planthopper, and can also be used to prevent and treat plant virus diseases such as TMV and CMV.

Synthesis and insecticidal activities of 2,3-dihydroquinazolin-4(1H)-one derivatives targeting calcium channel

A series of compounds containing dihydroquinazolinone moiety was designed and synthesized. Amine bridge part was changed in comparison with known anthranilic diamides insecticides. Their insecticidal activities against oriental armyworm (Mythimna separata) indicated that most of the compounds showed moderate to high activities at the tested concentrations. In particular, compounds 5a and 5k showed 80% larvicidal activities against oriental armyworm at the concentration of 5 mg/L. The present study also explored the possible effects of target compounds on the high voltage-gated calcium channel and the calcium channels in the endoplasmic reticulum in the central neurons isolated from the third instar larvae of Spodoptera exigua using whole-cell patch clamp and calcium imaging technique. The results showed that compound 5a activated the high voltage-gated calcium channel in the central neurons of S. exigua weakly. The peak currents only increased by 6% of the initial value at the end of the 10-min recording after treated with 0.22 μM 5a, while chlorantraniliprole has an opposite effect. The effects of 5a on the intracellular calcium ion concentration ([Ca2+]i) in neurons were well investigated. The experimental results indicated that these novel compounds have different mechanism compared with chlorantraniliprole.

Design, synthesis and biological activities of novel anthranilic diamide insecticide containing trifluoroethyl ether

Two series of novel anthranilic diamide insecticide containing trifluoroethyl ether were designed and synthesized, and their structures were characterized by 1H NMR spectroscopy, elemental analysis and single crystal X-ray diffraction analysis. The insecticidal activities of the new compounds were evaluated. The results of bioassays indicated that some of these title compounds exhibited excellent insecticidal activities. The insecticidal activities of compounds 19a, 19b, 19d, 19g, 19k and 19m against oriental armyworm at 2.5 mg·kg-1 were 100%. The larvicidal activities of 19a, 19b, 19c, 19d, 19e, 19g and 19n against diamond-back moth were 100% at 0.1 mg·kg-1. Surprisingly, most of them still exhibited perfect insecticidal activity against diamond-back moth when the concentration was reduced to 0.05 mg·kg-1, which was higher than the commercialized Chlorantraniliprole.