1006865-28-6

Basic information

• Product Name: (3R,4R,5S)-3-hydroxy-4-[4-(4-methoxy-butoxy)-phenyl]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester
• Synonyms: (3R,4R,5S)-3-hydroxy-4-[4-(4-methoxy-butoxy)-phenyl]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester
• CAS NO: 1006865-28-6
• Molecular Weight: 585.857
• Mol File: 1006865-28-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,4R,5S)-3-hydroxy-4-[4-(4-methoxy-butoxy)-phenyl]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5S)-3-hydroxy-4-[4-(4-methoxy-butoxy)-phenyl]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester(1006865-28-6)
• EPA Substance Registry System: (3R,4R,5S)-3-hydroxy-4-[4-(4-methoxy-butoxy)-phenyl]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester(1006865-28-6)

Safety Data

• Hazardous Substances Data: 1006865-28-6(Hazardous Substances Data)

Upstream product

• 873945-27-8 (3R,4R,5S)-3-hydroxy-4-(4-hydroxy-phenyl)-5-triisopropylsilanyl-oxy-piperidine-1-carboxylic acid benzyl ester 
• 4457-67-4 4-Methoxy-1-bromobutane 

Downstream Products

• 1006865-27-5 (3R,4R,5S)-4-[4-(4-methoxy-butoxy)-phenyl]-3-[4-(3-methoxy-propyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-5-triisopropylsilanyloxy-piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Organic compounds

The present invention relates to substituted piperidines of the general formula (I), where R1, R2, R3, R4, R5, Q and X have the definitions elucidated in more detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors. Moreover, the enzymatic substrate portion of the compound is simultaneously a substrate for a membrane transporter.