1006899-36-0

Basic information

• Product Name: 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione
• Synonyms: 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione
• CAS NO: 1006899-36-0
• Molecular Weight: 413.347
• Mol File: 1006899-36-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione(1006899-36-0)
• EPA Substance Registry System: 1-(2-amino-4-fluorobenzyl)-3-(4-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethylimidazolidine-2,4-dione(1006899-36-0)

Safety Data

• Hazardous Substances Data: 1006899-36-0(Hazardous Substances Data)

Upstream product

• 446-10-6 2-nitro-4-fluorotoluene 
• 1179329-78-2 1-(4-fluoro-2-nitrobenzyl)-3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethylimidazolidine-2,4-dione 
• 70842-04-5 5,5-dimethyl-3-(α,α,α,4-tetrafluoro-m-tolyl)hydantoin 
• 76437-44-0 1-(bromomethyl)-4-fluoro-2-nitrobenzene 
• 20274-69-5 (4-fluoro-3-nitrophenyl)methanol 

Downstream Products

• 1179329-83-9 N-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}N'-tert-butyloxycarbonylsulfamide 
• 1179329-41-9 diethyl [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonate 
• 1179329-43-1 [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonic acid 
• 1179329-84-0 N-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}sulfamide 
• 1179329-42-0 monoethyl [4-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)phenyl]phosphonate 
• 1179329-52-2 1-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}-3-(4-methanesulfonylphenyl)sulfamide 
• 1179906-55-8 methyl 2-(3-{5-fluoro-2-[3-(4-fluoro-3-trifluoromethylphenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-ylmethyl]phenyl}ureido)-2-methylpropionate 

Relevant articles and documents

Novel phenyl-substituted imidazolidines, process for preparation thereof, medicaments comprising said compounds and use thereof

The invention relates to compounds of formula (I) wherein the groups have stated meanings, and to their physiologically compatible salts. Said compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.

Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use

This invention relates to arylaminoaryl-alkyl-substituted imidazolidone-2,4-diones of formula (I) and also to their physiologically tolerated salts: Wherein R, R′, R1 to R10, A, D, E, G, L and p are as defined herein. The invention also relates to processes for preparing them, pharmaceutical compositions comprising them and their therapeutic use. The compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.