1007128-18-8Relevant articles and documents
An efficient and economical synthesis of 5-substituted 1 H -tetrazoles via Pb(II) salt catalyzed [3+2] cycloaddition of nitriles and sodium azide
Kant, Rama,Singh, Vishal,Agarwal, Alka
, p. 305 - 312 (2016)
A simple, mild and efficient method is developed for the synthesis of 5-substituted 1H-tetrazoles. Out of three used Pb(II) catalysts, lead chloride (PbCl2) has been found to be an efficient catalyst for [3+2] cycloaddition of NaN3 with aromatic and aliphatic nitriles to afford 5-substituted 1H-tetrazoles. The catalyst is reusable up to four cycles with consistent activity. The cost effectiveness and easy availability of the catalyst, simple methodology, excellent yield and easy work-up are the additional advantages.
Cadmium chloride as an efficient catalyst for neat synthesis of 5-substituted 1H-tetrazoles
Venkateshwarlu,Premalatha,Rajanna,Saiprakash
, p. 4479 - 4485 (2009)
Cadmium chloride (CdCl2) has been found to be an efficient catalyst for a neat [2+3]-cycloaddition of NaN3 with nitriles to afford 5-substituted 1H-tetrazoles in good yields. The shorter reaction times, greater yields of the product, and easy workup are the advantages of this methodology.
(NH4)2Ce(NO3)6 as an inexpensive, eco-friendly, efficient catalyst for the synthesis of 5-substituted 1-H tetrazoles from nitriles
Kumar, Satyanand,Dubey, Shristy,Saxena, Nisha,Awasthi, Satish Kumar
, p. 6034 - 6038 (2015/01/08)
Ceric ammonium nitrate (CAN) is found to be a suitable, inexpensive, and effective non-toxic catalyst for a smooth (3+2) cycloaddition of organic nitriles with NaN3 to afford 5-substituted 1H-tetrazoles in excellent yields. Shorter reaction times, easy work-up, and substantial and pure product formation are the key advantages of the present method.
