100725-70-0

Basic information

• Product Name: 4-phenacyl-nicotinic acid
• CAS NO: 100725-70-0
• Molecular Weight: 241.246
• Mol File: 100725-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-phenacyl-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenacyl-nicotinic acid(100725-70-0)
• EPA Substance Registry System: 4-phenacyl-nicotinic acid(100725-70-0)

Safety Data

• Hazardous Substances Data: 100725-70-0(Hazardous Substances Data)

Upstream product

• 100873-40-3 3-phenyl-pyrano[3,4-c]pyridin-1-one; hydrobromide 
• 119570-74-0 1-(2,6-dichloro-benzyl)-4-phenacylidene-1,4-dihydro-pyridine-3-carboxylic acid diethylamide 
• 3222-50-2 4-methylnicotinic acid 
• 611-74-5 N,N-dimethylbenzamide 

Downstream Products

• 141693-16-5 2-(2'-hydroxyethyl)-3-phenyl-1,2-dihydro-2,7-naphthyridin-1-one 
• 5657-55-6 3-phenyl-1H-pyrano(3,4-c)pyridin-1-one 

Relevant articles and documents

Application of organolithium and related reagents in synthesis. Part XI. Metallation of 2-methyl- and 4-methylnicotinic acids. A useful method for preparation of aza-isocoumarins

The metallation (LDA/THF) of 2-methyl- and 4-methylnicotinic acids (1) and (2), and the subsequent reaction of the lithiated species (3) and (4) with carbonyl electrophiles as a synthetic route of 5-aza- and 7-aza-isocoumarins (7), (8), (9) and (10), is d