1007404-14-9Relevant articles and documents
3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists
Biju, Purakkattle,Taveras, Arthur,Yu, Younong,Zheng, Junying,Chao, Jianhua,Rindgen, Diane,Jakway, James,Hipkin, R. William,Fossetta, James,Fan, Xuedong,Fine, Jay,Qiu, Hongchen,Merritt, J. Robert,Baldwin, John J.
, p. 228 - 231 (2008/09/17)
A series of novel and potent 3,4-diamino-2,5-thiadiazole-1-oxides were prepared and found to show excellent binding affinities for CXCR2 and CXCR1 receptors and excellent inhibitory activity of Gro-α and IL-8 mediated in vitro hPMN MPO release of CXCR2 an
