1008105-70-1Relevant articles and documents
Metal-Free One-Pot Synthesis of 3-Phosphinoylbenzofurans via Phospha-Michael Addition/Cyclization of H-Phosphine Oxides and in Situ Generated ortho-Quinone Methides
Du, Ji-Yuan,Ma, Yan-Hua,Yuan, Rui-Qing,Xin, Nana,Nie, Shao-Zhen,Ma, Chun-Lin,Li, Chen-Zhong,Zhao, Chang-Qiu
supporting information, p. 477 - 480 (2018/01/28)
A novel metal-free one-pot protocol for the effective and efficient synthesis of 3-phosphinoylbenzofurans via a phospha-Michael addition/cyclization of H-phosphine oxides and in situ generated ortho-quinone methides is described. Based on the expeditious
Synthesis of chromones through LiOtBu/air-mediated oxidation and regioselective cyclization of o-hydroxyphenyl propargyl carbinols
Zhang, Shuai,Wan, Changfeng,Wang, Qiang,Zhang, Baiqun,Gao, Lingfeng,Zha, Zhenggen,Wang, Zhiyong
, p. 2080 - 2083 (2013/05/09)
A cascade oxidative cyclization reaction for the synthesis of chromone derivatives was developed by using LiOtBu as a mediator and air as an oxidant. The reaction was carried out without the assistance of a transition metal under mild conditions to afford the chromones in good yields with high regioselectivities. A tandem reaction for the synthesis of various chromones was developed. LiOtBu was used as a mediator and air was used as a clean oxidant. The reaction generally showed high regioselectivity under mild conditions. Extensive research showed that dehydrogenative oxidation of the alcohols under strongly basic conditions was the crucial step, and Li+ was also found to play an important role in this process. Copyright
Versatile and expeditious synthesis of aurones via AuI-catalyzed cyclization
Harkat, Hassina,Blanc, Aurelien,Weibel, Jean-Marc,Pale, Patrick
, p. 1620 - 1623 (2008/09/16)
(Chemical Equation Presented) Aurones are conveniently formed in a three-step procedure including a goldI-catalyzed cyclization of 2-(1-hydroxyprop-2-ynyl)phenols as a highly regio- and stereoselective key step. A wide diversity of derivatives can be obtained starting from substituted salicylaldehydes. Synthesis of natural 4,6,3′,4′-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4′-chloroaurone) were achieved.