1008128-98-0Relevant articles and documents
Investigation of a flexible enantiospecific approach to aziridines
Jamookeeah, Clare E.,Beadle, Christopher D.,Jackson, Richard F. W.,Harrity, Joseph P. A.
, p. 1128 - 1130 (2008/09/18)
(Chemical Equation Presented) A flexible approach to functionalized and enantioenriched aziridines has been developed from an intermediate aziridinylmethyl tosylate. This protocol features a Cu-catalyzed Grignard substitution reaction that allows a range of functionalized organic fragments to be incorporated. Moreover, a convenient one-pot procedure is outlined that allows the trityl group to be exchanged for a range of common N-protecting groups.