100841-17-6 Usage
Molecular weight
283.4 g/mol This is the mass of one mole of the compound, calculated by adding the atomic weights of all the atoms in the molecular formula.
Structure
The compound has a total of 5 carbon atoms, with a primary alcohol (-OH) group attached to the first carbon atom, a methyl (-CH3) group attached to the fourth carbon atom, and a triphenylmethyl (-C6H5) group attached to the second carbon atom. The (S)designation indicates that the compound is a specific enantiomer, meaning that it has a specific three-dimensional shape that is mirror-image to a corresponding (R)enantiomer.
Physical properties
The physical properties of 1-Pentanol, 4-methyl-2-[(triphenylmethyl)amino]-, (S)are not provided in the material, but typically for a compound with this structure, it would be a solid at room temperature with a high melting and boiling point due to the presence of the bulky triphenylmethyl group.
Chemical properties
1-Pentanol, 4-methyl-2-[(triphenylmethyl)amino]-, (S)is a primary alcohol, meaning that the -OH group is attached to a carbon atom that is bonded to only one other carbon atom. This makes the -OH group reactive and easily removed in chemical reactions. The presence of the triphenylmethyl group makes the compound highly electron-rich, which can affect its reactivity in certain chemical reactions. Additionally, the (S)designation indicates that the compound is a chiral molecule, meaning that it can interact differently with other chiral molecules in chemical reactions.
Uses
1-Pentanol, 4-methyl-2-[(triphenylmethyl)amino]-, (S)is commonly used as a chiral resolving agent for various types of organic compounds, particularly those containing carboxylic acid groups. This means that it can be used to separate mixtures of different enantiomers, or mirror-image isomers, of a compound. The compound's structure and properties make it useful in a variety of chemical reactions and processes, particularly in the field of organic chemistry and synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 100841-17-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,4 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100841-17:
(8*1)+(7*0)+(6*0)+(5*8)+(4*4)+(3*1)+(2*1)+(1*7)=76
76 % 10 = 6
So 100841-17-6 is a valid CAS Registry Number.
100841-17-6Relevant articles and documents
Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids
Hall, Christopher J. J.,Goundry, William R. F.,Donohoe, Timothy J.
supporting information, p. 6981 - 6985 (2021/03/01)
For the first time we have been able to employ enantiopure 1,2-amino alcohols derived from abundant amino acids in C?C bond-forming hydrogen-borrowing alkylation reactions. These reactions are facilitated by the use of the aryl ketone Ph*COMe. Racemisation of the amine stereocentre during alkylation can be prevented by the use of sub-stoichiometric base and protection of the nitrogen with a sterically hindered triphenylmethane (trityl) or benzyl group. The Ph* and trityl groups are readily cleaved in one pot to give γ-aminobutyric acid (GABA) products as their HCl salts without further purification. Both steps may be performed in sequence without isolation of the hydrogen-borrowing intermediate, removing the need for column chromatography.
Improved Stereocontrolled Synthesis of Threo Peptidyl Epoxides
Albeck, Amnon,Persky, Rachel
, p. 653 - 657 (2007/10/02)
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Renin Inhibitors. Design of Angiotensinogen Transition-State Analogues Containing Novel (2R,3R,4R,5S)-5-Amino-3,4-dihydroxy-2-isopropyl-7-methyloctanoic Acid
Thaisrivongs, Suvit,Pals, Donald T.,Kroll, Lisa T.,Turner, Steve R.,Han, Fu-Son
, p. 976 - 982 (2007/10/02)
A highly stereoselective synthesis of 2(R)--3-methylbutyl>-2,2-dimethyl-4(R)-dioxolanyl>-3-methylbutanoic acid (11) is described.This is a suitably protected carboxylic acid useful as an intermediate for the prepa
