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1009083-66-2

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1009083-66-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1009083-66-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,9,0,8 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1009083-66:
(9*1)+(8*0)+(7*0)+(6*9)+(5*0)+(4*8)+(3*3)+(2*6)+(1*6)=122
122 % 10 = 2
So 1009083-66-2 is a valid CAS Registry Number.

1009083-66-2Relevant articles and documents

P2Y1 receptor antagonists as novel antithrombotic agents

Pfefferkorn, Jeffrey A.,Choi, Chulho,Winters, Thomas,Kennedy, Robert,Chi, Liguo,Perrin, Lisa A.,Lu, Gina,Ping, Yun-Wen,McClanahan, Tom,Schroeder, Richard,Leininger, Michael T.,Geyer, Andrew,Schefzick, Sabine,Atherton, James

body text, p. 3338 - 3343 (2009/04/06)

The P2Y1 and P2Y12 purinergic receptors are responsible for mediating adenosine diphosphate (ADP) dependent platelet aggregation. Evidence from P2Y1 knockout studies as well as from nucleotide-based small molecule P2Y1 antagonists has suggested that the antagonism of this receptor may offer a novel and effective method for the treatment of thrombotic disorders. Herein, we report the identification and optimization of a series of non-nucleotide P2Y1 antagonists that are potent and orally bioavailable.

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