100924-13-8

Basic information

• Product Name: (1S,3R,4R,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-(toluene-4-sulfonyl)-2-oxa-8-aza-bicyclo[4.2.0]octan-7-one
• CAS NO: 100924-13-8
• Molecular Weight: 686.145
• Mol File: 100924-13-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,3R,4R,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-(toluene-4-sulfonyl)-2-oxa-8-aza-bicyclo[4.2.0]octan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3R,4R,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-(toluene-4-sulfonyl)-2-oxa-8-aza-bicyclo[4.2.0]octan-7-one(100924-13-8)
• EPA Substance Registry System: (1S,3R,4R,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(tert-butyl-dimethyl-silanyloxymethyl)-8-(toluene-4-sulfonyl)-2-oxa-8-aza-bicyclo[4.2.0]octan-7-one(100924-13-8)

Safety Data

• Hazardous Substances Data: 100924-13-8(Hazardous Substances Data)

Upstream product

• 4083-64-1 Tosyl isocyanate 
• 79999-47-6 tri-O-(tert-butyldimethylsilyl)-D-glucal 

Downstream Products

• 100933-65-1 N-[(2R,3R,4R,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-tetrahydro-pyran-3-carbonyl]-4-methyl-benzenesulfonamide 

Relevant articles and documents

HIGH-PRESSURE (2+2)CYCLOADDITION OF TOLUENE-4-SULPHONYL ISOCYANATE TO GLYCALS

High-pressure (2+2)cycloaddition of toluene-4-sulphonyl isocyanate to glycals is examined.Reactions proceed regiospecifically to afford single products in case of all 3-substituted glycals.Upon heating or even after standing at room temperature adducts undergo retro-addition to give starting glycals.Various aspects of the cycloaddition are discussed, especially retro-reaction and rearrangement of β-lactams to α,β-unsaturated amides.