1009318-28-8

Basic information

• Product Name: 3-(2-methoxyphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 3-(2-methoxyphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
• CAS NO: 1009318-28-8
• Molecular Weight: 330.386
• Mol File: 1009318-28-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(2-methoxyphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-methoxyphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one(1009318-28-8)
• EPA Substance Registry System: 3-(2-methoxyphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one(1009318-28-8)

Safety Data

• Hazardous Substances Data: 1009318-28-8(Hazardous Substances Data)

Upstream product

• 118-48-9 isatoic anhydride 
• 90-04-0 2-methoxy-phenylamine 
• 100-52-7 benzaldehyde 
• 64001-48-5 2-(sulfinylamino)benzoyl chloride 
• 5877-56-5 (E)-N-benzylidene-2-methoxybenzenamine 

Relevant articles and documents

CuO nanoparticles catalyzed simple and efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones under ultrasound irradiation in aqueous ethanol under ultrasound irradiation in aqueous ethanol

A CuO nanoparticle-catalyzed one-pot process has engineered for the preparation of diverse quinazolinones from the readily available isatoic anhydride, aldehydes and amine or ammonium. For amine substrates the reactions afford 2,3-dihydroquinazolin-4(1H)-ones in aqueous ethanol promoted by ultrasound irradiation. However, the ammonium substrates undergo intramolecular electron transfer and rearrangement yielding quinazolin-4(3H)-ones. The catalyst is recyclable four times without loss of substantial activity. Other remarkable features include the wide range of functional group tolerance (46 quinazolinones are synthesized and 9 of them are reported firstly), and providing moderate to excellent yield of the products under mild conditions.

Microwave assisted eco-friendly protocol for one pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones in water

An efficient one pot L-proline catalyzed multicomponent synthesis of 2,3-dihydro-4(1H)-quinazolinones has been achieved involving isatoic anhydride, aldehyde and amine or ammonium acetate in water under microwave. The use of Lproline, water and MW has pro

On the reaction of anthranilic acid with thionyl chloride: Iminoketene intermediate formation

2-(Sulfinylamino) benzoyl chloride is formed on treating anthranilic acid with thionyl chloride. The formation of iminoketene intermediate from 2-(sulfinylamino) benzoyl chloride is established and the reactions carried out using the intermediate are described.