101020-41-1Relevant articles and documents
AN ENANTIOSELECTIVE SYNTHESIS OF THE CARZINOPHILIN DEGRADATION PRODUCT (2S,3S) 4-AMINO-2,3-DIHYDROXY-3-METHYLBUTYRIC ACID
Garner, Philip,Park, Jung Min,Rotello, Vicent
, p. 3299 - 3302 (1985)
An efficient, enantioselective synthesis of (2S,3S) 4-amino-2,3-dihydroxy-3-methylbutyric acid (1) is described.The sequence includes the direct use of azide to selectively open a secondary epoxy alcohol formed under Payne rearrangement conditions.