101041-28-5

Basic information

• Product Name: 1-(3,4-dimethoxybenzyl)-5,6-dimethoxy-2,3-dihydro-1H-indene
• Synonyms: 1-(3,4-dimethoxybenzyl)-5,6-dimethoxy-2,3-dihydro-1H-indene
• CAS NO: 101041-28-5
• Molecular Weight: 328.408
• Mol File: 101041-28-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,4-dimethoxybenzyl)-5,6-dimethoxy-2,3-dihydro-1H-indene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-dimethoxybenzyl)-5,6-dimethoxy-2,3-dihydro-1H-indene(101041-28-5)
• EPA Substance Registry System: 1-(3,4-dimethoxybenzyl)-5,6-dimethoxy-2,3-dihydro-1H-indene(101041-28-5)

Safety Data

• Hazardous Substances Data: 101041-28-5(Hazardous Substances Data)

Upstream product

• 13074-31-2 Tetrahydropapaverine 
• 185-80-8 1-oxa-2-azaspiro[2.5]octane 

Relevant articles and documents

N-Atom Deletion in Nitrogen Heterocycles

Excising the nitrogen in secondary amines, and coupling the two residual fragments is a skeletal editing strategy that can be used to construct molecules with new skeletons, but which has been largely unexplored. Here we report a versatile method of N-atom excision from N-heterocycles. The process uses readily available N-heterocycles as substrates, and proceeds by N-sulfonylazidonation followed by the rearrangement of sulfamoyl azide intermediates, providing various cyclic products. Examples are provided of deletion of nitrogen from natural products, synthesis of chiral O-heterocycles from commercially available chiral β-amino alcohols, formal inert C?H functionalization through a sequence of N-directed C?H functionalization and N-atom deletion reactions in which the N-atom can serve as a traceless directing group.