101079-83-8

Basic information

• Product Name: Benzene, 1-chloro-2-(chloromethyl)-4-methoxy-
• CAS NO: 101079-83-8
• Molecular Formula: C8H8Cl2O
• Molecular Weight: 191.057
• Mol File: 101079-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-2-(chloromethyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-2-(chloromethyl)-4-methoxy-(101079-83-8)
• EPA Substance Registry System: Benzene, 1-chloro-2-(chloromethyl)-4-methoxy-(101079-83-8)

Safety Data

• Hazardous Substances Data: 101079-83-8(Hazardous Substances Data)

Upstream product

• 824-98-6 m-methoxybenzyl chloride 
• 6280-89-3 2-chloro-5-methoxybenzoic acid 
• 54810-63-8 methyl (2-chloro-5-methoxy)benzoate 
• 101252-66-8 (2-chloro-5-methoxyphenyl)methanol 

Downstream Products

• 36707-27-4 1,2-bis(3-methoxyphenyl)ethane 
• 34322-78-6 3-(m-methoxyphenyl)propan-2-ol 
• 51755-56-7 (3-methoxybenzyl)trimethylsilane 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 
• 119055-88-8 19-(2-chloro-5-methoxyphenyl)-3,3-(2,2-dimethyltrimethylenedioxy)-9(11)-androstene-5α,17β-diol 

Relevant articles and documents

Methoxy-substituted α, n-didehydrotoluenes. photochemical generation and polar vs diradical reactivity

The photoreactivity of differently substituted (chloromethoxybenzyl)trimethylsilanes in alcohols and alcohol/water mixtures has been investigated by means of a combined computational and experimental approach. Subsequent elimination of the chloride anion and the trimethylsilyl cation gives the corresponding methoxy-substituted α,n-didehydrotoluenes (α,n-MeO-DHTs). The rate of desilylation is evaluated through the competition with arylation via phenyl cation (ca. 108s-1). α,2-MeO- and α,4-MeO-DHTs show a purely radical behavior (H abstraction from the solvent, methanol), while α,3-MeO-DHT shows mainly a ionic chemistry, as when the parent α,3-DHT is thermally generated. This is likely due to triplet-singlet surfaces crossing occurring during desilylation.