101080-26-6

Basic information

• Product Name: 2-amino-5-bromo-3-chloro-benzoic acid methyl ester
• Synonyms: 2-amino-5-bromo-3-chloro-benzoic acid methyl ester
• CAS NO: 101080-26-6
• Molecular Weight: 264.506
• Mol File: 101080-26-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-5-bromo-3-chloro-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-bromo-3-chloro-benzoic acid methyl ester(101080-26-6)
• EPA Substance Registry System: 2-amino-5-bromo-3-chloro-benzoic acid methyl ester(101080-26-6)

Safety Data

• Hazardous Substances Data: 101080-26-6(Hazardous Substances Data)

Usage

Parent Compound

2-amino-5-bromo-3-chloro-benzoic acid

Parent Compound Type

Derivative of benzoic acid

Functional Groups

Methyl ester, amino, bromo, chloro

Usage

Organic synthesis, pharmaceutical research

Applications

Pharmaceuticals, agrochemicals, other industries

Structure Characteristics

Valuable for creating new molecules

Potential

Developing new applications in chemical and pharmaceutical fields

Upstream product

• 77820-58-7 methyl 3-chloroanthranilate 
• 6388-47-2 2-amino-3-chlorobenzoic acid 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 

Relevant articles and documents

Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators

Neurotensin receptor 1 (NTR1) is a G protein coupled receptor that is widely expressed throughout the central nervous system where it acts as a neuromodulator. Neurotensin receptors have been implicated in a wide variety of CNS disorders, but despite extensive efforts to develop small molecule ligands there are few reports of such compounds. Herein we describe the optimization of a quinazoline based lead to give 18 (SBI-553), a potent and brain penetrant NTR1 allosteric modulator.