1011464-57-5

Basic information

• Product Name: prop-1-en-2-yl 3-tert-butyl-1-phenyl-1H-pyrazol-5-ylcarbamate
• Synonyms: prop-1-en-2-yl 3-tert-butyl-1-phenyl-1H-pyrazol-5-ylcarbamate
• CAS NO: 1011464-57-5
• Molecular Weight: 299.373
• Mol File: 1011464-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: prop-1-en-2-yl 3-tert-butyl-1-phenyl-1H-pyrazol-5-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: prop-1-en-2-yl 3-tert-butyl-1-phenyl-1H-pyrazol-5-ylcarbamate(1011464-57-5)
• EPA Substance Registry System: prop-1-en-2-yl 3-tert-butyl-1-phenyl-1H-pyrazol-5-ylcarbamate(1011464-57-5)

Safety Data

• Hazardous Substances Data: 1011464-57-5(Hazardous Substances Data)

Upstream product

• 57933-83-2 Isopropenyl chloroformate 
• 126208-61-5 5-amino-1-phenyl-3-tert-butylpyrazole 

Relevant articles and documents

KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The present invention relates to novel kinase inhibitors and modulator compounds useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferrably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.