1011481-34-7

Basic information

• Product Name: methyl {(2S,4R)-1-[(1S)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pent-2-yn-1-yl]-2-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetate
• Synonyms: methyl {(2S,4R)-1-[(1S)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pent-2-yn-1-yl]-2-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetate
• CAS NO: 1011481-34-7
• Molecular Weight: 491.517
• Mol File: 1011481-34-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl {(2S,4R)-1-[(1S)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pent-2-yn-1-yl]-2-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl {(2S,4R)-1-[(1S)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pent-2-yn-1-yl]-2-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetate(1011481-34-7)
• EPA Substance Registry System: methyl {(2S,4R)-1-[(1S)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pent-2-yn-1-yl]-2-[4-(trifluoromethyl)phenyl]piperidin-4-yl}acetate(1011481-34-7)

Safety Data

• Hazardous Substances Data: 1011481-34-7(Hazardous Substances Data)

Upstream product

• 917-92-0 3,3-Dimethylbut-1-yne 
• 406-87-1 4,4,4-trifluorobutanal 
• 1261170-90-4 C₈H₈O₃*C₁₅H₁₈F₃NO₂ 
• 884602-78-2 (+)-methyl {(2S,4R)-2-[4-(trifluoromethyl)phenyl]-4-piperidinyl}acetate 

Downstream Products

• 1011481-35-8 methyl {(2S,4R)-1-[(1R)-4,4-dimethyl-1-(3,3,3-trifluoropropyl)pentyl]-2-[4-(trifluoromethyI)phenyl]piperidin-4-yl}acetate 

Relevant articles and documents

Fluorinated piperidine acetic acids as γ-secretase modulators

We report herein a novel series of difluoropiperidine acetic acids as modulators of γ-secretase. Synthesis of 2-aryl-3,3-difluoropiperidine analogs was facilitated by a unique and selective β-difluorination with Selectfluor. Compounds 1f and 2c were selec