101204-49-3 Usage
Description
2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is a chemical compound that functions as a P2Y1 receptor antagonist. It is characterized by its unique structure, which includes a 2'-deoxyribose sugar moiety, a methylated adenine base, and two phosphate groups at the 3' and 5' positions. 2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT is soluble in water and has potential applications in various fields, particularly in the study and treatment of diseases related to the P2Y1 receptor.
Uses
Used in Pharmaceutical Research:
2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is used as a P2Y1 receptor antagonist for the investigation of the receptor's role in various physiological and pathological processes. By blocking the P2Y1 receptor, this compound can help researchers understand the receptor's function and its potential as a therapeutic target for certain diseases.
Used in Cardiovascular Research:
In porcine coronary small arteries, 2'-deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is used as a P2Y1 receptor antagonist to study the receptor's involvement in vascular function and its potential role in the regulation of blood flow and blood pressure.
Used in Cellular Biology:
2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is used as a P2Y1 receptor antagonist in endothelial cells to explore the receptor's role in cell signaling, adhesion, and migration, which are crucial for maintaining vascular integrity and function.
Used in Neuroscience:
In hippocampal astrocytes, 2'-deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is used as a P2Y1 receptor antagonist to investigate the receptor's involvement in glial cell function, which may have implications for understanding and treating neurological disorders associated with astrocyte dysfunction.
Overall, 2'-deoxy-N6-methyladenosine 3',5'-bisphosphate tetraammonium salt is a valuable tool in the study of the P2Y1 receptor and its role in various biological processes, with potential applications in the development of new therapeutic strategies for diseases related to this receptor.
Biological Activity
A competitive antagonist at P2Y 1 receptors (K B = 100 nM). Selective over P2X 1 (IC 50 = 1.15 μ M), P2X 3 (IC 50 = 12.9 μ M), P2X 2 , P2X 4 , P2Y 2 , P2Y 4 and P2Y 6 receptors.
Biochem/physiol Actions
MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality.
Check Digit Verification of cas no
The CAS Registry Mumber 101204-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,2,0 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 101204-49:
(8*1)+(7*0)+(6*1)+(5*2)+(4*0)+(3*4)+(2*4)+(1*9)=53
53 % 10 = 3
So 101204-49-3 is a valid CAS Registry Number.