1012057-92-9

Basic information

• Product Name: 6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexan-1-ol
• Synonyms: 6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexan-1-ol
• CAS NO: 1012057-92-9
• Molecular Weight: 419.883
• Mol File: 1012057-92-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexan-1-ol(1012057-92-9)
• EPA Substance Registry System: 6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexan-1-ol(1012057-92-9)

Safety Data

• Hazardous Substances Data: 1012057-92-9(Hazardous Substances Data)

Upstream product

• 4286-55-9 1-bromo-6-hexanol 
• 184475-71-6 4-(3-chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline 

Downstream Products

• 1012057-93-0 N-acetoxy-N-(6-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)hexyl)acetamide 

Relevant articles and documents

MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS

The present invention relates to the compositions, methods, and applications of a novel approach to selective inhibition of several cellular or molecular targets with a single small molecule. More specifically, the present invention relates to multi-functional small molecules wherein one functionality is capable of inhibiting histone deacetylases (HDAC) and the other functionality is capable of inhibiting a different cellular or molecular pathway involved in aberrant cell proliferation, differentiation or survival.