1012058-32-0

Basic information

• Product Name: (Z)-methyl 4-(2-(5-((5-fluoro-2-oxo-indolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethoxy)benzoate
• Synonyms: (Z)-methyl 4-(2-(5-((5-fluoro-2-oxo-indolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethoxy)benzoate
• CAS NO: 1012058-32-0
• Molecular Weight: 477.492
• Mol File: 1012058-32-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-methyl 4-(2-(5-((5-fluoro-2-oxo-indolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethoxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-methyl 4-(2-(5-((5-fluoro-2-oxo-indolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethoxy)benzoate(1012058-32-0)
• EPA Substance Registry System: (Z)-methyl 4-(2-(5-((5-fluoro-2-oxo-indolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethoxy)benzoate(1012058-32-0)

Safety Data

• Hazardous Substances Data: 1012058-32-0(Hazardous Substances Data)

Upstream product

• 56850-93-2 methyl 4-(2-Aminoethyloxy)benzoate 
• 356068-93-4 5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 

Relevant articles and documents

SUBSTITUTED 2-INDOLINONE AS PTK INHIBITORS CONTAINING A ZINC BINDING MOIETY

The present invention relates to substituted 2-indolinone containing zinc- binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.