101225-88-1 Usage
Description
N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide is a chemical compound that belongs to the class of phthalimide derivatives. It is characterized by the presence of a phthalimide group and a 1,2,4-triazole ring, which are connected through a propyl spacer. N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide exhibits potential bioactive properties and serves as a valuable building block in medicinal chemistry for the synthesis of various pharmaceutical compounds. Its chemical structure allows for modification and optimization to enhance specific biological activities, making it a versatile and promising candidate in drug discovery and development.
Uses
Used in Pharmaceutical Industry:
N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide is used as a building block for the synthesis of pharmaceutical compounds due to its potential bioactive properties and versatile chemical structure. It can be modified and optimized to target specific biological activities, making it a valuable asset in the development of new drugs.
Used in Medicinal Chemistry:
N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide is used as a key component in the design and synthesis of novel pharmaceutical compounds with anti-inflammatory and analgesic properties. Its potential as a drug candidate for the treatment of various diseases and conditions makes it an important compound in the field of medicinal chemistry.
Used in Drug Discovery and Development:
N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide is utilized in drug discovery and development processes due to its potential bioactive properties and the ability to modify its chemical structure for specific biological activities. N-(3-[1,2,4]triazol-1-yl-propyl)-phthalimide holds promise in the development of new therapeutic agents for a wide range of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 101225-88-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,2,2 and 5 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 101225-88:
(8*1)+(7*0)+(6*1)+(5*2)+(4*2)+(3*5)+(2*8)+(1*8)=71
71 % 10 = 1
So 101225-88-1 is a valid CAS Registry Number.
101225-88-1Relevant articles and documents
Evaluation of synthetic substituted 1,2-dioxanes as novel agents against human leishmaniasis
Ortalli,Varani,Rosso,Quintavalla,Lombardo,Trombini
, p. 126 - 140 (2019)
The treatment of human leishmaniasis is currently based on few compounds that are highly toxic, expensive and have a high rate of treatment failure. A number of recent studies on new drugs focuses on natural or semi-synthetic compounds. Among them, the endoperoxide artemisinin, extracted from Artemisia annua, and some of its derivatives have shown leishmanicidal activity. In the present work, a series of structurally simple, fully synthetic 1,2-dioxanes were evaluated for in vitro antileishmanial activity against promastigotes of Leishmania donovani; the cytotoxicity for mammalian cells was also assessed. The six most promising compounds in terms of activity and selectivity were further investigated for their antileishmanial activity on the promastigote forms of L. tropica, L. major and L. infantum and against L. donovani amastigotes. The good performance in terms of potency and selectivity makes these six hits promising candidates for a preliminary lead optimization as antileishmanial agents.
