101259-36-3Relevant articles and documents
Thioalkylation of Enolates, III. Stereoselective Synthesis of Steroids and Related Compounds, II. α-Thioalkylation of Zinc Dienolates to 4-Substituted 1-tert-Butoxy-7a-methyl-hexahydroinden-5-ones
Groth, Ulrich,Koehler, Thomas,Taapken, Thomas
, p. 665 - 668 (2007/10/02)
α-Alkylation of the α,β-unsaturated ketone 1 at C-4 has been achieved by thioalkylation of the corresponding zinc dienolate with α-chlorosulfides of type 2.The desulfurization of the β-(phenylthio)ketones 4 leads directly to the 4-substituted hexahydroind
ZINC(II)-CHLORIDE INDUCED THIOALKYLATION OF ALUMINIUM ENOLATES; ENANTIOSELECTIVE SYNTHESIS OF ESTRADIOL-3-METHYL-17-tert-BUTYL DIETHER
Groth, Ulrich,Koehler, Thomas,Taapken, Thomas
, p. 7583 - 7592 (2007/10/02)
Zinc(II)-chloride induced thioalkylation of the aluminium enolate 6 generated by conjugate reduction of the enone 5 leads - directly or via its trimethylsilylenol ether 6 - to alkylated hydrindanones 10 which are important intermediates in the synthesis o