101351-11-5

Basic information

• Product Name: 3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole
• Synonyms: 3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole
• CAS NO: 101351-11-5
• Molecular Weight: 282.299
• Mol File: 101351-11-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole(101351-11-5)
• EPA Substance Registry System: 3-ethoxycarbonyl-5-(2-furyl)-1-phenylpyrazole(101351-11-5)

Safety Data

• Hazardous Substances Data: 101351-11-5(Hazardous Substances Data)

Upstream product

• 36983-35-4 ethyl 4-(furan-2-yl)-2,4-dioxobutyrate 
• 100-63-0 phenylhydrazine 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 100537-55-1 5-[2]furyl-1-phenyl-1H-pyrazole-3-carboxylic acid 
• 100873-83-4 5-[2]furyl-1-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid 

Relevant articles and documents

Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole

A series of chromone derivatives containing substituted pyrazole were designed and synthesized. Preliminary bioassays showed that most of the synthesized compounds exhibited good nematicidal activity in vivo against Meloidogyne incognita at 10 mg/L. Among the tested compounds, A10 and A11 exhibited 100% inhibition rates. In addition, the molecular docking results indicated that both compound A10 and A11 interacts with amino acid residue Tyr121, Trp279, Tyr70, Trp84 and Phe330 of AChE via hydrogen bond and π–π stacking. This investigation suggested that the chromone containing substituted pyrazole scaffold could be further optimized to explore novel, high-bioactivity nematicidal leads.