101386-38-3

Basic information

• Product Name: (R)-2-[1-Ethoxycarbonylmethyl-2-oxo-1,4,5,6-tetrahydro-2H-benzo[b]azocin-(3E)-ylideneamino]-4-phenyl-butyric acid ethyl ester
• CAS NO: 101386-38-3
• Molecular Weight: 464.561
• Mol File: 101386-38-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-[1-Ethoxycarbonylmethyl-2-oxo-1,4,5,6-tetrahydro-2H-benzo[b]azocin-(3E)-ylideneamino]-4-phenyl-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[1-Ethoxycarbonylmethyl-2-oxo-1,4,5,6-tetrahydro-2H-benzo[b]azocin-(3E)-ylideneamino]-4-phenyl-butyric acid ethyl ester(101386-38-3)
• EPA Substance Registry System: (R)-2-[1-Ethoxycarbonylmethyl-2-oxo-1,4,5,6-tetrahydro-2H-benzo[b]azocin-(3E)-ylideneamino]-4-phenyl-butyric acid ethyl ester(101386-38-3)

Safety Data

• Hazardous Substances Data: 101386-38-3(Hazardous Substances Data)

Upstream product

• 97278-72-3 3-azido-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one 
• 91167-28-1 3-bromo-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one 
• 22246-75-9 3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one 
• 46460-23-5 ethyl 2-amino-4-phenyl-(2S)-butyrate 
• 93749-43-0 1-(carbethoxymethyl)-3,4,5,6-tetrahydro<1>benzazocine-2,3(1H)-dione 

Downstream Products

• 97278-79-0 (3S)-1-(carboxymethyl)-3-<<(1S)-1-carboxy-3-phenylpropyl>amino>-3,4,5,6-tetrahydro-<1>benzazocin-2(1H)-one hydrochloride 
• 97278-79-0 (3S)-1-(carboxymethyl)-3-<<(1S)-1-carboxy-3-phenylpropyl>amino>-3,4,5,6-tetrahydro-<1>benzazocin-2(1H)-one hydrochloride 
• 97278-77-8 (3S)-1-(carbethoxymethyl)-3-<<(1S)-1-(ethoxycarbonyl)-3-phenylpropyl>amino>-3,4,5,6-tetrahydro-<1>benzazocin-2(1H)-one 
• 97278-78-9 (3R)-1-(carbethoxymethyl)-3-<<(1S)-1-(ethoxycarbonyl)-3-phenylpropyl>amino>-3,4,5,6-tetrahydro-<1>benzazocin-2(1H)-one 

Relevant articles and documents

Synthesis and biological properties of (carboxyalkyl)amino-substituted bicyclic lactam inhibitors of angiotensin converting enzyme

Syntheses of the potent angiotensin converting enzyme inhibitor (3S)-1-(carboxymethyl)-3-[[(1S)-1-carboxy-3-phenylpropyl]amino]-2,3,4,5 -tetrahydro-1H-[1]benzazepin-2-one (CGS 14831) and the related monoester prodrug (17a; CGS 14824A) are described together with preparative details for six- and eight-membered ring analogues. Inhibitory potencies and in vivo biological activity of the compounds are discussed. The data indicate that 17a has a biological profile comparable to that of enalapril.