1014977-87-7

Basic information

• Product Name: N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea
• Synonyms: N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea
• CAS NO: 1014977-87-7
• Molecular Weight: 683.317
• Mol File: 1014977-87-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(1014977-87-7)
• EPA Substance Registry System: N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea(1014977-87-7)

Safety Data

• Hazardous Substances Data: 1014977-87-7(Hazardous Substances Data)

Upstream product

• 1014977-81-1 N-(4-chlorobenzyl)-N'-(3-phenylpropionyl)thiourea 
• 152030-49-4 3-(1-trityl-1H-imidazol-4-yl)propan-1-ol 

Downstream Products

• 1014977-97-9 N-(4-chlorobenzyl)-S-{3-[1-(triphenylmethyl)imidazol-4-yl]propyl}isothiourea 
• 3538-68-9 3-phenylpropanehydrazide 

Relevant articles and documents

Efficient approaches to S-alkyl-N-alkylisothioureas: Syntheses of histamine H3 antagonist clobenpropit and its analogues

(Chemical Equation Presented) S-Alkyl-N-alkylisothioureas were efficiently synthesized via synthetic approach (A) using 3-phenylpro-pionyl isothiocyanate (PPI). The utility of the approach was proved by the syntheses of clobenpropit, a potent histamine H3 antagonist, and its analogues. Alternatively, clobenpropit could be prepared via intramolecular amide cleavage (B) with use of 2-nitrophenylacetyl isothiocyanate (NPAI).