101565-92-8

Basic information

• Product Name: Adenosine, N-(3-thienylMethyl)-
• Synonyms: Adenosine, N-(3-thienylMethyl)-
• CAS NO: 101565-92-8
• Molecular Formula: C15H17N5O4S
• Molecular Weight: 363.39158
• EINECS: -0
• Mol File: 101565-92-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Adenosine, N-(3-thienylMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-(3-thienylMethyl)-(101565-92-8)
• EPA Substance Registry System: Adenosine, N-(3-thienylMethyl)-(101565-92-8)

Safety Data

• Hazardous Substances Data: 101565-92-8(Hazardous Substances Data)

Upstream product

• 2004-06-0 6-Chloropurine riboside 
• 27757-86-4 (3-thienylmethyl)amine 
• 498-62-4 3-thiophene carboxaldehyde 
• 42466-50-2 3-thiophenecarbaldoxime hydrochloride 

Relevant articles and documents

COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN

Compounds for use in prevention and treatment of neurodegenerative disease and pain are disclosed. In one embodiment of the invention, the compound is selected from the group consisting of N6-[(3-halothien-2-yl)methyl]adenosine, N6-[(4-halothien-2-yl)methyl]adenosine, and N6-[(5-halothien-2-yl)methyl]adenosine. In another embodiment of the invention, the compound is selected from the group consisting of N6-[(2-bromothien-3-yl)methyl]adenosine, N6-[(4-bromothien-3-yl)methyl]adenosine, N6-[(5-bromothien-3-yl)methyl]adenosine N6-[(2-chlorothien-3-yl)methyl]adenosine, N6-[(4-chlorothien-3-yl)methyl]adenosine, and N6-[(5-chlorothien-3-yl)methyl]adenosine. Also disclosed are methods of making and using the same.

COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN

Compounds for use in prevention and treatment of neurodegenerative disease and pain are disclosed. In one embodiment of the invention, the compound is selected from the group consisting of N66-[(3-halothien-2-yl)methyl]adenosine, N66-[(4-halothien-2-yl)methyl]adenosine, and N66-[(5-halothien-2-yl)methyl]adenosine. In another embodiment of the invention, the compound is selected from the group consisting of N66-[(2-bromothien-3-yl)methyl]adenosine, N66-[(4-bromothien-3-yl)methyl]adenosine, N66-[(5-bromothien-3-yl)methyl]adenosine N66-[(2-chlorothien-3-yl)methyl]adenosine, N66-[(4-chlorothien-3-yl)methyl]adenosine, and N66-[(5-chlorothien-3-yl)methyl]adenosine. Also disclosed are methods of making and using the same.

N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF

The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.