101596-43-4

Basic information

• Product Name: Benzofuran, 2-ethyl-3-(phenylmethyl)-
• CAS NO: 101596-43-4
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• Mol File: 101596-43-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzofuran, 2-ethyl-3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 2-ethyl-3-(phenylmethyl)-(101596-43-4)
• EPA Substance Registry System: Benzofuran, 2-ethyl-3-(phenylmethyl)-(101596-43-4)

Safety Data

• Hazardous Substances Data: 101596-43-4(Hazardous Substances Data)

Upstream product

• 877-35-0 2-bromo-1-phenylbutan-1-one 
• 1346667-98-8 1-phenyl-2-(2-phenylethynylphenoxy)butan-1-one 
• 1346667-93-3 2-(2-iodophenoxy)-1-phenylbutan-1-one 
• 101596-60-5 (2-ethyl-benzofuran-3-yl)-phenyl-methanol 
• 3131-63-3 2-ethylbenzofuran 
• 1486-50-6 4-(benzyloxy)benzoic acid chloride 

Downstream Products

• 848690-86-8 1-(3-benzyl-2-ethyl-benzofuran-6-yl)-propan-1-one 

Relevant articles and documents

tert-BuOK-mediated carbanion-yne intramolecular cyclization: Synthesis of 2-substituted 3-benzylbenzofurans

A mild, efficient, and regioselective carbanion-yne intramolecular cyclization mediated by t-BuOK for the synthesis of 2-substituted 3-benzylbenzofurans is developed. It was started from o-iodophenol (1), based on O-alkylation, and the Sonogashira reaction in sequence to produce 2-(2-phenylethynylphenoxy)-1-arylalkanones (5). An intramolecular carbanion-yne 5-exo-dig cyclization reaction of 5, which was mediated by t-BuOK, yielded title benzofurans in good yields.