1016645-42-3

Basic information

• Product Name: [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid
• Synonyms: [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid
• CAS NO: 1016645-42-3
• Molecular Weight: 427.44
• Mol File: 1016645-42-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid(1016645-42-3)
• EPA Substance Registry System: [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid(1016645-42-3)

Safety Data

• Hazardous Substances Data: 1016645-42-3(Hazardous Substances Data)

Upstream product

• 1016645-41-2 methyl [{[2-(4-amino-3-nitrophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetate 
• 833486-94-5 4-amino-3-nitrophenylboronic acid pinacol ester 

Relevant articles and documents

Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors

The invention relates to new compounds having heptose synthesis inhibitory properties, of formula (I) or a pharmaceutically acceptable salt, or prodrug thereof, wherein A is an aryl or heterocycle, optionally substituted by one or several identical or different R such as H, C1-C10 alkyl, C1-C10 alkyl-OR1, C1-C10 alkyl-NR1R1, alkoxy, hydroxy, thioalkyl, aryl, heterocycle, halogen, nitro, cyano, CO2R1, NR1R1, NR1C(O)R1, C(O)NR1R1, NR1C(S)R1, C(S)NR1R1, SO2NR1R1, SO2R1, NR1SO2R1, NR1C(O)NR1R1, NR1C(O)OR1, NR1C(S)NR1R1, NR1C(S)OR1, R1C═NOR1, C(O)R1, aryloxy, thioaryl, alkenyl, alkynyl R1 identical or different is H or C1-C10 alkyl B1, B2, B3 identical or not represent C, N, O, S to form a five-membered aromatic ring wherein from one to three carbon atoms are replaced by a heteroatom selected from S, O, N optionally substituted by one or several identical or different R such as defined above B4 is C or N Y is H, C1-C10 alkyl, alkoxy, thio-alkyl, optionally substituted by one or several identical or different R such as defined above W is C, O or N, substituted or not by one or several C1-C10 alkyl radicals D is an heterocycle optionally substituted by one or several identical or different R such as defined above.