1016778-99-6

Basic information

• Product Name: N-(3-amino-4-methylphenyl)propane-1-sulfonamide
• Synonyms: N-(3-amino-4-methylphenyl)propane-1-sulfonamide
• CAS NO: 1016778-99-6
• Molecular Weight: 228.315
• Mol File: 1016778-99-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3-amino-4-methylphenyl)propane-1-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-amino-4-methylphenyl)propane-1-sulfonamide(1016778-99-6)
• EPA Substance Registry System: N-(3-amino-4-methylphenyl)propane-1-sulfonamide(1016778-99-6)

Safety Data

• Hazardous Substances Data: 1016778-99-6(Hazardous Substances Data)

Upstream product

• 1269421-30-8 N-(4-methyl-3-nitrophenyl)propane-1-sulfonamide 
• 1269421-29-5 N-(4-methyl-3-nitrophenyl)-N-(propylsulfonyl)propane-1-sulfonamide 
• 119-32-4 4-Methyl-3-nitroanilin 

Downstream Products

• 1396311-01-5 N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)propane-1-sulfonamide 

Relevant articles and documents

Protein kinase inhibitor and its composition and use thereof

The invention relates to compounds as shown in the general formula (I), pharmaceutical compositions containing the compounds, a method for treating diseases and disease symptoms related to abnormal activity of protein kinase by using the compounds, and medicinal use of the compounds.

HETEROCYCLIC SULFONAMIDES AS RAF INHIBITORS

Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I), stereoisomers, tautomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.