101680-98-2

Basic information

• Product Name: 2-diphenylphosphinoyl-5-hydroxy-1-phenylpentan-1-one
• Synonyms: 2-diphenylphosphinoyl-5-hydroxy-1-phenylpentan-1-one
• CAS NO: 101680-98-2
• Molecular Weight: 378.408
• Mol File: 101680-98-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-diphenylphosphinoyl-5-hydroxy-1-phenylpentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-diphenylphosphinoyl-5-hydroxy-1-phenylpentan-1-one(101680-98-2)
• EPA Substance Registry System: 2-diphenylphosphinoyl-5-hydroxy-1-phenylpentan-1-one(101680-98-2)

Safety Data

• Hazardous Substances Data: 101680-98-2(Hazardous Substances Data)

Upstream product

• 114856-27-8 Methyl 4-diphenylphosphinoylbutanoate 
• 6399-81-1 triphenylphosphine hydrobromide 
• 73367-76-7 4-Diphenylphosphinoylbutanoic acid 
• 891-97-4 δ-diphenylphosphorylbutyl alcohol 
• 101680-95-9 4-diphenylphosphinoylbutyl benzoate 

Downstream Products

• 122552-35-6 2-(Diphenyl-phosphinoyl)-1-phenyl-pentane-1,5-diol 
• 13159-16-5 (E)-5-phenyl-4-penten-1-ol 

Relevant articles and documents

ACYL TRANSFER REACTIONS WITH PHOSPHINE OXIDES: SYNTHESIS OF E-HOMOALLYLIC ALCOHOLS, CYCLOPROPYL KETONES, AND γ-HYDROXY KETONES

Esters of 3-hydroxypropylphosphine oxides rearrange in base by O to C acyl (RCO) transfer to give the hydroxy ketones (8). threo-Selective reduction of (8) leads to pure E-homoallylic alcohols whilst C to O acyl )Ph2PO) transfer leads to γ-hydroxy ketones with nucleophilic aqueous base or cyclopropyl ketones with BuOKt - HOBut.