1016927-51-7

Basic information

• Product Name: 3-(4,5-dihydro-1H-imidazol-2-yl)benzonitrile
• Synonyms: 3-(4,5-dihydro-1H-imidazol-2-yl)benzonitrile
• CAS NO: 1016927-51-7
• Molecular Weight: 171.202
• Mol File: 1016927-51-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-(4,5-dihydro-1H-imidazol-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4,5-dihydro-1H-imidazol-2-yl)benzonitrile(1016927-51-7)
• EPA Substance Registry System: 3-(4,5-dihydro-1H-imidazol-2-yl)benzonitrile(1016927-51-7)

Safety Data

• Hazardous Substances Data: 1016927-51-7(Hazardous Substances Data)

Upstream product

• 626-17-5 benzene-1,3-dicarbonitrile 
• 107-15-3 ethylenediamine 

Relevant articles and documents

Trichloroisocyanuric acid as an efficient homogeneous catalyst for the chemoselective synthesis of 2-substituted oxazolines, imidazolines and thiazolines under solvent-free condition

Trichloroisocyanuric acid, as a commercially available and inexpensive catalyst, was used in a new, facile and efficient procedure for the synthesis of 2-oxazolines, 2-imidazolines and 2-thiazolines through the reaction of nitriles with 2-aminoethanol, ethylenediamine or 2-aminoethanethiol under solvent-free conditions.

Microwave-assisted cascade cycloaddition for C-N bond formation: An approach to the construction of 1,4,5,6-tetrahydropyrimidine and 2-imidazoline derivatives

An efficient strategy for the synthesis of various 1,4,5,6- tetrahydropyrimidine and 2-imidazoline derivatives has been reported. The reactions proceeded from nitriles with ethylenediamine or 1,3-diaminopropane via cascade cycloaddition in the presence of CuL2 (L = 2-hydroxy-2-phenylacetate) to afford the corresponding 1,4,5,6- tetrahydropyrimidine or 2-imidazoline derivatives under reflux conditions or microwave irradiation in excellent yields.

Copper-catalyzed synthesis of 2-imidazolines and their N-hydroxyethyl derivatives under various conditions

A rapid and efficient method for the synthesis of 2-imidazolines and their N-hydroxyethyl derivatives from the reaction of aromatic nitriles with ethylenediamine (EDA) or N-(2-aminoethyl)ethanolamine (AEEA) using cupric indole-3-acetate (Cu(II)-(IAA)2) as a reusable catalyst under reflux and microwave conditions is reported. And seven new N-hydroxyethyl-imidazolines were reported for the first time.