101716-49-8

Basic information

• Product Name: N-(quinolin-3-yl)cinnamamide
• Synonyms: N-(quinolin-3-yl)cinnamamide
• CAS NO: 101716-49-8
• Molecular Weight: 274.322
• Mol File: 101716-49-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(quinolin-3-yl)cinnamamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(quinolin-3-yl)cinnamamide(101716-49-8)
• EPA Substance Registry System: N-(quinolin-3-yl)cinnamamide(101716-49-8)

Safety Data

• Hazardous Substances Data: 101716-49-8(Hazardous Substances Data)

Upstream product

• 580-17-6 3-aminoquinoline 
• 140-10-3 (E)-3-phenylacrylic acid 
• 102-92-1 Cinnamoyl chloride 

Relevant articles and documents

Boric Acid Catalyzed Direct Amidation between Amino-Azaarenes and Carboxylic Acids

A novel and facile boric acid catalyzed direct amidation between amino-azaarene compounds and carboxylic acids has been developed. The amidation proceeded cleanly and provided good to excellent yields of the desired amides. Boric acid is a green and inexpensive catalyst. We have also found that N,N,N′,N′-tetramethylpropane-1,3-diamine acted as an additive accelerating this boric acid catalyzed amidation. A mixed acid anhydride is postulated to be the active intermediate responsible for this successful amidation. This direct amidation is an atom- and step-economical reaction.