10177-15-8 Usage
Description
5-phenylpyridine-3-carboxamide, also known as Fenazon, is a chemical compound with the molecular formula C12H9N3O. It is a versatile building block in the pharmaceutical industry and has potential applications in the development of new cancer treatments, as well as in the treatment of inflammatory conditions and pain management.
Uses
Used in Pharmaceutical Industry:
5-phenylpyridine-3-carboxamide is used as a building block for the synthesis of various pharmaceutical agents and drugs. Its unique structure and properties make it a valuable component in the development of new medications.
Used in Cancer Treatment:
5-phenylpyridine-3-carboxamide is used as a potential inhibitor for a number of protein kinases, making it a promising candidate for the development of new cancer treatments. Its ability to target specific kinases could lead to more effective therapies with fewer side effects.
Used in Anti-inflammatory and Analgesic Applications:
5-phenylpyridine-3-carboxamide has demonstrated anti-inflammatory and analgesic properties, making it valuable for the treatment of various inflammatory conditions and pain management. Its potential to alleviate inflammation and pain could improve the quality of life for patients suffering from these conditions.
Overall, 5-phenylpyridine-3-carboxamide has a wide range of potential applications in the pharmaceutical and medical fields, offering new opportunities for the development of innovative treatments and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 10177-15-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,7 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10177-15:
(7*1)+(6*0)+(5*1)+(4*7)+(3*7)+(2*1)+(1*5)=68
68 % 10 = 8
So 10177-15-8 is a valid CAS Registry Number.
10177-15-8Relevant articles and documents
A method for preparing the amide compounds
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Paragraph 0034; 0035, (2017/02/09)
The invention discloses a method for preparing an amide compound. The method includes the following specific step: raw materials of a cyano compound and a boric acid compound are heated for a cyan hydrolysis reaction and a carbon-carbon coupling reaction with a mixed solvent of a protic solvent and a non protonic solvent as the reaction medium, in the air atmosphere and in the presence of alkali and a palladium compound catalyst, so as to prepare the amide compound. The novel method for preparing amide compound disclosed by the invention avoids the usage of an oxidant in the prior art, so as to effectively inhibit the excessive hydrolysis of cyano group, avoid further hydrolysis of amide into carboxylic acid, and greatly improve the reaction yield of the amide compound; and the method can be carried out simultaneously with the carbon-carbon coupling reaction to prepare more amide compounds, and has great market value and economic benefit for industrial production of amide compounds.
Efficient coupling of heteroaryl halides with arylboronic acids in the presence of a palladium-tetraphosphine catalyst
Feuerstein, Marie,Doucet, Henri,Santelli, Maurice
, p. 327 - 336 (2007/10/03)
Cis, cis, cis-1,2,3,4-tetrakis(diphenylphosphinomethyl) cyclopentane: ·1/2[PdCl(C3H5)]2 system catalyses the Suzuki cross-coupling of heteroaryl halides with a range of arylboronic acids with very high ratio substrate/catalyst in good yields. Substrates such as pyridines, quinolines, thiophenes, an indole, pyrimidines or a furane have been used successfully.
