101803-03-6 Usage
Description
N2-ETHYL-2'-DEOXYGUANOSINE, also known as 2'-Deoxy-N-ethylguanosine, is an acetaldehyde-derived DNA adduct that forms in human leukocyte DNA of healthy individuals after alcohol consumption. This adduct is a result of the reaction between acetaldehyde, a toxic byproduct of alcohol metabolism, and the DNA molecule, leading to potential genetic alterations and health implications.
Uses
Used in Medical Research:
N2-ETHYL-2'-DEOXYGUANOSINE is used as a biomarker for alcohol consumption in healthy individuals. Its presence in leukocyte DNA can help researchers understand the effects of alcohol on the human body and potentially identify early signs of alcohol-related health issues.
Used in Toxicology Studies:
N2-ETHYL-2'-DEOXYGUANOSINE is used as a research tool in toxicology studies to investigate the mechanisms of acetaldehyde-induced DNA damage and its role in the development of various diseases, including cancer and liver diseases.
Used in Drug Development:
N2-ETHYL-2'-DEOXYGUANOSINE can be used as a target for the development of therapeutic agents aimed at preventing or reversing the formation of this DNA adduct, potentially reducing the harmful effects of alcohol consumption on the human body.
Used in Forensic Science:
N2-ETHYL-2'-DEOXYGUANOSINE can be used as an indicator of alcohol exposure in forensic investigations, helping to determine the presence and extent of alcohol consumption in individuals involved in legal cases.
Check Digit Verification of cas no
The CAS Registry Mumber 101803-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,8,0 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 101803-03:
(8*1)+(7*0)+(6*1)+(5*8)+(4*0)+(3*3)+(2*0)+(1*3)=66
66 % 10 = 6
So 101803-03-6 is a valid CAS Registry Number.
