101865-40-1

Basic information

• Product Name: N-(2-(piperidine-1-carbonyl)phenyl)piperidine-1-carboxamide
• Synonyms: N-(2-(piperidine-1-carbonyl)phenyl)piperidine-1-carboxamide
• CAS NO: 101865-40-1
• Molecular Weight: 315.415
• Mol File: 101865-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-(piperidine-1-carbonyl)phenyl)piperidine-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(piperidine-1-carbonyl)phenyl)piperidine-1-carboxamide(101865-40-1)
• EPA Substance Registry System: N-(2-(piperidine-1-carbonyl)phenyl)piperidine-1-carboxamide(101865-40-1)

Safety Data

• Hazardous Substances Data: 101865-40-1(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 110-89-4 piperidine 
• 524-38-9 N-hydroxyphthalimide 
• 57212-70-1 N-(mesyloxy)phthalimide 

Relevant articles and documents

Ring opening of N-hydroxyphthalimide to construct phenylurea derivatives

Arylurea and their analogues have been one of the most ubiquitous backbone during the past century, and extensive studies have been conducted to establish practical synthetic methods for their derivatives. In particular, it is an effective pathway to synthesize arylureas by using commercially available phthalimide compounds. Reported herein is a triethoxyphosphine promoted ring-opening of the N-hydroxyphthalimide (NHPI) by the nucleophilic attack of amines. This transformation shows a wide range of functional-group tolerance under mild reaction conditions.