1018898-84-4

Basic information

• Product Name: L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)-
• Synonyms: L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)-;(3S,4R,5S,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate
• CAS NO: 1018898-84-4
• Molecular Formula: C₂₈H₃₁ClO₁₀
• Molecular Weight: 562.99274
• Mol File: 1018898-84-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)-(1018898-84-4)
• EPA Substance Registry System: L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)-(1018898-84-4)

Safety Data

• Hazardous Substances Data: 1018898-84-4(Hazardous Substances Data)

Usage

General Description

L-Xylopyranose, 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 1,2,3,4-tetraacetate,(5S)- is a chemical compound composed of a xylopyranose sugar molecule that has been modified with four acetyl groups and a substituted benzene ring. The compound is chiral, with the (5S)- configuration. It is commonly used in pharmaceutical research and development, particularly in the study of carbohydrate chemistry and drug design. The compound's specific structure and properties make it valuable for understanding the interactions between sugars and other molecules in biological systems, as well as for potentially developing new therapeutic agents.

Upstream product

• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 281652-58-2 2-chloro-5-iodobenzoylchloride 
• 19094-56-5 2-chloro-5-iodobenzoic acid 
• 1103738-30-2 (4-chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuran[2,3-d][1,3]dioxolan-5-yl)methanone 
• 1103738-29-9 1-chloro-2-(4-ethoxybenzyl)-4-iodobenzene 
• 1103738-26-6 (2-chloro-5-iodo-phenyl)-(4-ethoxyphenyl)methanone 
• 1352955-16-8 (3aS,5R,6S,6aS)-5-hydroxymethyl-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxolane-6-ol 
• 1103738-17-5 (3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxolane-5-carboxylic acid 
• 1103738-19-7 ((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholin-4-yl)methanone 
• 108-21-4 Isopropyl acetate 

Downstream Products

• 1018898-85-5 acetic acid (2S,3S,4R,5S,6S)-4,5-diacetoxy-2-bromo-6-[4-chloro-3-(4-ethoxy-benzyl)-phenyl]-tetrahydropyran-3-yl ester 
• 1018898-93-5 (2S,3R,4S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate 
• 461432-26-8 dapagliflozin 

Relevant articles and documents

6-halogenated glucose C-glycoside as well as preparation method and application thereof

The invention discloses a 6-halogenated glucose C-glycoside as well as a preparation method and application thereof. A structure of 6-halogenated glucose C-glycoside is shown in formula I; an intermediate can be synthesized efficiently with cheap and easily available raw materials; meanwhile, when the raw material is used for synthesizing Jardiance, dapagliflozin and the like, a reaction yield ishigh, and an obtained product has high purity and relatively high industrial application prospect.

SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE

Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.

METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS

Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I: