101953-62-2

Basic information

• Product Name: 2-(4-methyl-1-homopiperazino)-1H-benzimidazole
• Synonyms: 2-(4-methyl-1-homopiperazino)-1H-benzimidazole
• CAS NO: 101953-62-2
• Molecular Weight: 230.313
• Mol File: 101953-62-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-methyl-1-homopiperazino)-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methyl-1-homopiperazino)-1H-benzimidazole(101953-62-2)
• EPA Substance Registry System: 2-(4-methyl-1-homopiperazino)-1H-benzimidazole(101953-62-2)

Safety Data

• Hazardous Substances Data: 101953-62-2(Hazardous Substances Data)

Upstream product

• 4318-37-0 1-Methylhomopiperazine 
• 4857-06-1 2-chloro-1H-benzoimidazole 

Relevant articles and documents

Synthesis of benzimidazole derivatives as antiallergic agents with 5- lipoxygenase inhibiting action

Syntheses were conducted of novel benzimidazole derivatives that suppress histamine release from mast cells, inhibit 5-lipoxygenase, and possess antioxidative action. Among the compounds synthesized, 1-[2-[2-(4- hydroxy-2,3,5-trimethylphenoxy)ethoxy]ethyl]-2-(4-methyl-1- homopiperazino)benzimidazole (22) potently suppressed histamine release from rat peritoneal mast cells triggered by the antigen-antibody reaction, inhibited 5-lipoxygenase in rat basophilic leukemia-1 (RBL-1) cells, and prevented the NADPH-dependent lipid peroxidation induced by Fe3+-ADP in rat liver microsomes, in addition to an antagonizing the contraction of guinea pig ileum caused by histamine.