10196-30-2

Basic information

• Product Name: 2-AMINO-2-METHYLBUTAN-1-OL
• Synonyms: 2-AMINO-2-METHYLBUTAN-1-OL;1-Butanol, 2-amino-2-methyl-
• CAS NO: 10196-30-2
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.164
• Mol File: 10196-30-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-2-METHYLBUTAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-2-METHYLBUTAN-1-OL(10196-30-2)
• EPA Substance Registry System: 2-AMINO-2-METHYLBUTAN-1-OL(10196-30-2)

Safety Data

• Hazardous Substances Data: 10196-30-2(Hazardous Substances Data)

Usage

General Description

2-AMINO-2-METHYLBUTAN-1-OL, also known as 2-amino-2-methyl-1-butanol or α-aminoisobutyric acid, is a chemical compound with the molecular formula C5H13NO. It is a colorless, liquid organic compound with a slightly ammoniacal odor. This chemical is primarily used as a chiral building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a corrosion inhibitor and as a component in the production of polymers and resins. Additionally, 2-AMINO-2-METHYLBUTAN-1-OL has potential applications in fuel additives and as a solvent for a variety of organic compounds.

Upstream product

• 77392-55-3 2-methyl-2-nitro-butan-1-ol 
• 56247-82-6 α-ethylalanine ethyl ester 
• 563-46-2 2-Methyl-1-butene 
• 595-39-1 DL-isovaline 
• 1565-80-6 (2S)-2-methyl-1-butanol 
• 3059-97-0 (2R)-2-amino-2-methylbutanoic acid 

Relevant articles and documents

Electroorganic chemistry; 145: Coupling reaction of an olefin with a radical NO.3 generated by anodic oxidation of NO-3

When NO-3 is electrochemically oxidized in the presence of a variety of terminal and 1,2-disubstituted olefins 1 in a mixed solvent system (MeCN:H2O:Et2O = 10:2:1), a radical NO.3 is generated from NO-3 and nitrate esters 3 are formed by a new coupling reaction of the olefin with the radical. The products 3 can be further transformed into the corresponding alcohols 4 and alkyl iodides 5. Under the same reaction conditions, 1,1-di- and 1,1,2-trisubstituted olefins 6 do not give nitrate esters but afford oxazoline derivatives 7. (1S,5S)-(-)-β-Pinene (13) is diastereoselectively transformed into (1S,2R,5S)-(-)-myrtanol (14) by this technique.

Palladium-catalyzed ring opening of isoprene monoxide with nitrogen nucleophiles - Asymmetric synthesis of branched amino sugars

The Pd-catalyzed regio- and enantioselective ring opening of isoprene monoxide with primary amines as pronucleophiles is developed with good yield and enantioselectivity, constructing a quaternary stereocenter enantioselectively. This methodology was used

The use of alpha-amino acids in the synthesis of derivatives of 2-aminoethanethiol as potential antiradiation agents.

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