1019999-18-8

Basic information

• Product Name: Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin
• Synonyms: Mono-6-O-(2-naphthyl)-per-O-methyl-α-cyclodextrin;XRGIJNKZLAFOQY-UHFFFAOYSA-N
• CAS NO: 1019999-18-8
• Molecular Formula: C63H100O30
• Molecular Weight: 1337.4501
• EINECS: -0
• Mol File: 1019999-18-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin(CAS DataBase Reference)
• NIST Chemistry Reference: Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin(1019999-18-8)
• EPA Substance Registry System: Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin(1019999-18-8)

Safety Data

• Hazardous Substances Data: 1019999-18-8(Hazardous Substances Data)

Usage

Description

Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin is a chemical compound derived from alpha-cyclodextrin, a cyclic oligosaccharide consisting of seven glucose units. It is modified with a 2-naphthyl group at the 6-O position and has all hydroxyl groups methylated. This modification enhances its solubility and interaction with various molecules, making it a versatile compound for different applications.

Uses

Used in Mass Spectrometry:
Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin is used as a mass calibration standard in MALDI-TOF-MS (Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry) for accurate mass determination of biomolecules. Its well-defined structure and mass provide a reliable reference for calibrating the mass spectrometer, ensuring precise measurements in various research and diagnostic applications.
If there are additional applications in different industries, they can be listed as follows:
Used in Pharmaceutical Industry:
Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin can be used as a complexation agent for improving the solubility and bioavailability of poorly water-soluble drugs. Its hydrophobic cavity can accommodate a wide range of drug molecules, facilitating their encapsulation and enhancing their dissolution rate, which is crucial for drug absorption and efficacy.
Used in Analytical Chemistry:
In the field of analytical chemistry, Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin can be employed as a chiral selector for the separation of enantiomers in chromatographic techniques such as HPLC (High-Performance Liquid Chromatography) and GC (Gas Chromatography). Its unique structure allows for the selective interaction with enantiomers, enabling the resolution of racemic mixtures and providing valuable information on the stereochemistry of chiral compounds.
Used in Environmental Science:
Mono-6-O-(2-naphthyl)-per-O-methyl-alpha-cyclodextrin can also be utilized in environmental science for the removal of pollutants from water and soil. Its hydrophobic cavity can selectively bind to various organic contaminants, facilitating their extraction and concentration, which can then be followed by further treatment or disposal. This application contributes to the development of more sustainable and effective methods for environmental remediation.