102-19-2 Usage
Description
Isopentyl phenylacetate, also known as isoamyl phenylacetate, is an organic compound with a sweet, pleasant odor reminiscent of cocoa with a slight birch-tar undertone. It is characterized by its warm rosy honey taste with phenyl chocolate nuances and dried fruit notes when present at 5 to 10 ppm. Isopentyl phenylacetate can be synthesized by esterification of phenylacetic acid with isoamyl alcohol in the presence of concentrated sulfuric acid or by heating benzyl nitrile and isoamyl alcohol in the presence of excess concentrated H2SO4. It has been reported to be found in peppermint oil.
Uses
Used in Flavor and Fragrance Industry:
Isopentyl phenylacetate is used as a flavoring agent for its sweet, pleasant odor reminiscent of cocoa with a slight birch-tar undertone. Its warm rosy honey taste with phenyl chocolate nuances and dried fruit notes make it a desirable addition to the flavor industry.
Used in Aromatherapy:
Isopentyl phenylacetate is used as an aromatherapy agent due to its sweet, honey, chocolate aroma with a rosy floral nuance at 1% concentration. Its pleasant and soothing scent can be utilized in various aromatherapy applications to promote relaxation and well-being.
Used in Cosmetics and Personal Care Products:
Isopentyl phenylacetate is used as a fragrance ingredient in cosmetics and personal care products, such as perfumes, lotions, and creams, to provide a pleasant and long-lasting scent.
Used in the Food Industry:
Isopentyl phenylacetate can be used as an additive in the food industry to enhance the flavor of various products, particularly those with a chocolate or cocoa base, due to its sweet, pleasant odor reminiscent of cocoa.
Preparation
By esterification of phenylacetic acid with isoamyl alcohol in the presence of concentrated sulfuric acid; by heating benzyl
nitrile and isoamyl alcohol in the presence of excess concentrated H2SO4
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 102-19-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 2 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 102-19:
(5*1)+(4*0)+(3*2)+(2*1)+(1*9)=22
22 % 10 = 2
So 102-19-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O2/c1-11(2)8-9-15-13(14)10-12-6-4-3-5-7-12/h3-7,11H,8-10H2,1-2H3
102-19-2Relevant articles and documents
Structure activity relationship of organic alcohol and esters for antidepressant-like activity
Perveen, Shahnaz,Yasmeen, Arfa,Khan, Muhammad Aitmaud,Dar, Ahsana,Jafri, Rehana,Ahmed, Amir
experimental part, p. 14 - 17 (2011/01/03)
The synthesized compounds 1-7 were evaluated for their antidepressant activity, among which 2-phenylethyl alcohol 1 and isoamyl phenylacetate 3 showed 43 % and 37 % reduction in immobility time in mice using forced swim test, thereby, displaying antidepressant-like activity. Compound 1 and 3 were equipotent and both these compounds were 2x effective than the standard drug phenelzine. Considering other esters it appears that a decrease in alkyl chain length or addition of either NO2 or OH groups to the phenyl ring caused a marked decline in the antidepressant-like activity.
Esterification in dry media using ferric perchlorate adsorbed on silica gel
Parmar, Anupama,Kaur, Jatinder,Goyal, Rita,Kumar, Baldev,Kumar, Harish
, p. 2821 - 2826 (2007/10/03)
Adsorption of Fe(ClO4)3(H2O)6 onto chromatographic grade silica gel in the presence of alcohol ( to be used for esterification ) produces a supported reagent, Fe(ClO4)3(ROH)6/SiO2. This reagent, has been found effective for the rapid and high yield of esters, on grinding in the presence of carboxylic acids using pestle and mortar in the solid state.
Transesterification of methyl arylacetates wtih lithium alkoxides
Bhawal,Khanapure,Biehl
, p. 112 - 114 (2007/10/02)
A series of methyl arylacetates were transesterified in excellent yields using lithium alkoxides derived from primary, secondary, and tertiary aliphatic alcohols, benzyl alcohols, and allyl alcohol.
