102012-60-2

Basic information

• Product Name: 3-(5-benzyloxy-indol-3-yl)-propionic acid ethyl ester
• Synonyms: 3-(5-benzyloxy-indol-3-yl)-propionic acid ethyl ester
• CAS NO: 102012-60-2
• Molecular Weight: 323.392
• Mol File: 102012-60-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(5-benzyloxy-indol-3-yl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-benzyloxy-indol-3-yl)-propionic acid ethyl ester(102012-60-2)
• EPA Substance Registry System: 3-(5-benzyloxy-indol-3-yl)-propionic acid ethyl ester(102012-60-2)

Safety Data

• Hazardous Substances Data: 102012-60-2(Hazardous Substances Data)

Upstream product

• 52068-30-1 4-benzyloxyphenylhydrazine hydrochloride 
• 7358-97-6 5-benzyloxy-3-(2-carboxy-ethyl)-indole-2-carboxylic acid 
• 7394-76-5 3-(5-benzyloxy-indol-3-yl)-propionic acid 

Relevant articles and documents

Anhydrous Hydrogen Iodide-Mediated Reductive Indolization of in Situ-Generated Cyclopropyl Hydrazones

Fischer-type indolization of N-aryl-C-cyclopropyl hydrazones generated in situ followed by chemoselective reduction using tert-butyl iodide as an anhydrous HI generator was developed. This protocol provides indoles bearing carboxylic acid derivative units. A series of control experiments indicated the HI-mediated formation and reduction of spirocyclopropyl indolenines. Anhydrous HI functions as a Br?nsted acid as well as a reducing agent, facilitating the successful conversion of unstable reaction intermediates and iodinated mixtures in equilibrium.