1020192-59-9

Basic information

• Product Name: (S)-(2-(4-nitrophenyl)-4,5-dihydrooxazol-5-yl)methanol
• Synonyms: (S)-(2-(4-nitrophenyl)-4,5-dihydrooxazol-5-yl)methanol
• CAS NO: 1020192-59-9
• Molecular Weight: 222.2
• Mol File: 1020192-59-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-(2-(4-nitrophenyl)-4,5-dihydrooxazol-5-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(2-(4-nitrophenyl)-4,5-dihydrooxazol-5-yl)methanol(1020192-59-9)
• EPA Substance Registry System: (S)-(2-(4-nitrophenyl)-4,5-dihydrooxazol-5-yl)methanol(1020192-59-9)

Safety Data

• Hazardous Substances Data: 1020192-59-9(Hazardous Substances Data)

Upstream product

• 88229-26-9 N-(2-propen-1-yl)-4-nitrobenzamide 
• 122-04-3 4-nitro-benzoyl chloride 
• 61278-21-5 (S)-3-Amino-1,2-propanediol 
• 619-72-7 4-nitrobenzonitrile 

Relevant articles and documents

Stereoselective Oxidative Cyclization ofN-Allyl Benzamides to Oxaz(ol)ines

This study presents an enantioselective oxidative cyclization ofN-allyl carboxamides via a chiral triazole-substituted iodoarene catalyst. The method allows the synthesis of highly enantioenriched oxazolines and oxazines, with yields of up to 94% and enantioselectivities of up to 98% ee. Quaternary stereocenters can be constructed and, besidesN-allyl amides, the corresponding thioamides and imideamides are well tolerated as substrates, giving rise to a plethora of chiral 5-memberedN-heterocycles. By applying a multitude of further functionalizations, we finally demonstrate the high value of the observed chiral heterocycles as strategic intermediates for the synthesis of other enantioenriched target structures.