102022-17-3

Basic information

• Product Name: 1-phenyl-4-(quinolin-2-yl)butan-1-one
• Synonyms: 1-phenyl-4-(quinolin-2-yl)butan-1-one
• CAS NO: 102022-17-3
• Molecular Weight: 275.35
• Mol File: 102022-17-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-phenyl-4-(quinolin-2-yl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-4-(quinolin-2-yl)butan-1-one(102022-17-3)
• EPA Substance Registry System: 1-phenyl-4-(quinolin-2-yl)butan-1-one(102022-17-3)

Safety Data

• Hazardous Substances Data: 102022-17-3(Hazardous Substances Data)

Upstream product

• 91-63-4 2-methylquinoline 
• 100-58-3 phenylmagnesium bromide 
• 71-43-2 benzene 
• 29636-75-7 3-bromo-1-phenylpropan-1-one 
• 58521-76-9 2-(2-bromoethyl)-2-phenyl-[1,3]dioxolane 
• 1323154-02-4 2-(3-(2-phenyl-1,3-dioxolan-2-yl)propyl)quinoline 
• 63487-23-0 β-N,N-dimethylaminoethylquinaldine 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 772-03-2 2-vinylquinoline 
• 98-86-2 acetophenone 

Relevant articles and documents

Silver-Promoted Radical Ring-Opening/Pyridylation of Cyclobutanols with N-Methoxypyridinium Salts

The silver-promoted reaction of tertiary cyclobutanols with N-methoxypyridinium salts enables the efficient synthesis of a range of C2-substituted pyridines. The overall process likely occurs by ring-opening (via β-scission) of the cyclobutoxy radical to generate the corresponding γ-keto alkyl radical that itself adds to the pyridinium salt. A wide range of tertiary cyclobutanols and N-methoxypyridinium salts are compatible with the reaction conditions.

Enantioselective synthesis of quinolizidines and indolizidines via a catalytic asymmetric hydrogenation cascade

A catalytic enantioselective synthesis of a new class of quinolizidines and indolizidines is presented. An asymmetric Bronsted acid catalyzed hydrogenation cascade as well as a sequential Bronsted acid/metal catalyzed hydrogenation protocol of 2-substituted quinolines yields benzofused quinolizidines and indolizidines in good yields with high diastereo- and enantioselectivities. Georg Thieme Verlag Stuttgart - New York.