1020540-98-0

Basic information

• Product Name: 4-trifluoromethyl-6-phenyl-2-acetylaminopyrimidine
• Synonyms: 4-trifluoromethyl-6-phenyl-2-acetylaminopyrimidine
• CAS NO: 1020540-98-0
• Molecular Weight: 281.237
• Mol File: 1020540-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-trifluoromethyl-6-phenyl-2-acetylaminopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-trifluoromethyl-6-phenyl-2-acetylaminopyrimidine(1020540-98-0)
• EPA Substance Registry System: 4-trifluoromethyl-6-phenyl-2-acetylaminopyrimidine(1020540-98-0)

Safety Data

• Hazardous Substances Data: 1020540-98-0(Hazardous Substances Data)

Upstream product

• 5699-40-1 acetylguanidine 

Downstream Products

• 26974-09-4 2-amino-4-phenyl-6-(trifluoromethyl)pyrimidine 

Relevant articles and documents

One-pot synthesis of N2-aminoprotected 6-substituted and cycloalka[d] 4-trifluoromethyl-2-acetylaminopyrimidines

(Chemical Equation Presented) The one-pot synthesis of a novel series of amino-protected 6-alkyl-, 6-aryl-, 6-heteroaryl- and 5,6-fused-cycloalkane 4-trifluoromethyl-2-acetylaminopyrimidines, where alkyl = Me; aryl = Ph, 4-CH3Ph, 4-FPh, 4-ClPh, 4-BrPh, 4-OCH3Ph, 4-NO 2Ph, 4,4′-biphenyl, 1-naphthyl; heteroaryl = 2-thienyl, 2-furyl and cycloalkyl = c-C6H4, c-C7H5 from the reaction of substituted 4-methoxy-1,1,1-trifluoroalk-3-en-2-ones with 1-acetylguanidine in acetonitrile or propan-2-ol as solvent, is reported. The acetylamino group of 2-acetylaminopyrimidines was hydrolyzed under three different conditions to afford the corresponding free 2-aminopyrimidines.